E-ISSN 3041-4156
 
2024, Vol: 1, Issue: 1
1 / 1Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Review Article

Online Publishing Date:
27 / 02 / 2024



An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review

Suvendu Kumar Sahoo, Samyuktha Metta.


Abstract
This review delves into the use of natural super disintegrating agents in pharmaceutical drug formulations. Disintegrants are incorporated into these formulations to aid in breaking down tablets and capsules, promoting rapid dissolution by facilitating their dispersion into smaller particles. Super disintegrants, distinguished by their notable swelling capacity, play a pivotal role in expediting drug disintegration within the gastrointestinal tract. The selection of an appropriate super disintegrant hinges on several factors, including chemical compatibility, swelling potential, disintegration speed, particle size, cost, manufacturing methods, and adherence to regulatory standards. The piece elucidates the diverse mechanisms through which super disintegrants foster the disintegration of solid dosage forms. These mechanisms encompass swelling, wicking, heat-induced wetting, chemical reactions, particle repulsion, and deformation recovery. A comprehensive grasp of super disintegrants' properties and mechanisms is indispensable for ensuring the effectiveness, safety, and cost-efficiency of drug formulations. This review article critically examines existing literature, offering a valuable resource for researchers and pharmaceutical professionals engaged in the development of efficient and safe pharmaceutical products.

Key words: Natural super disintegrating agents, Disintegration mechanism, Formulations.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Suvendu Kumar Sahoo
Articles by Samyuktha Metta
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Sahoo SK, Metta S. An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. J Pharmacol Pharm Res. 2024; 1(1): 21-31. doi:10.5455/JPPR.20240107023841

Web Style

Sahoo SK, Metta S. An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. https://www.scopub.com/jppr/?mno=302657556 [Access: February 29, 2024]. doi:10.5455/JPPR.20240107023841

AMA (American Medical Association) Style

Sahoo SK, Metta S. An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. J Pharmacol Pharm Res. 2024; 1(1): 21-31. doi:10.5455/JPPR.20240107023841


Vancouver/ICMJE Style

Sahoo SK, Metta S. An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. J Pharmacol Pharm Res. (2024), [cited February 29, 2024]; 1(1): 21-31. doi:10.5455/JPPR.20240107023841


Harvard Style

Sahoo, S. K. & Metta, . S. (2024) An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. J Pharmacol Pharm Res, 1 (1), 21-31. doi:10.5455/JPPR.20240107023841


Turabian Style

Sahoo, Suvendu Kumar, and Samyuktha Metta. 2024. An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. Journal of Pharmacological and Pharmaceutical Research, 1 (1), 21-31. doi:10.5455/JPPR.20240107023841


Chicago Style

Sahoo, Suvendu Kumar, and Samyuktha Metta. "An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review." Journal of Pharmacological and Pharmaceutical Research 1 (2024), 21-31. doi:10.5455/JPPR.20240107023841


MLA (The Modern Language Association) Style

Sahoo, Suvendu Kumar, and Samyuktha Metta. "An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review." Journal of Pharmacological and Pharmaceutical Research 1.1 (2024), 21-31. Print. doi:10.5455/JPPR.20240107023841


APA (American Psychological Association) Style

Sahoo, S. K. & Metta, . S. (2024) An Exploration of The Potential of Natural Super Disintegrating Agents in Pharmaceutical Formulations: A Review. Journal of Pharmacological and Pharmaceutical Research, 1 (1), 21-31. doi:10.5455/JPPR.20240107023841


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesTerms of UseLicense InformationCopyright Information

About Journal of Pharmacological and Pharmaceutical Research

Journal of Pharmacological and Pharmaceutical Research is an international, peer-reviewed, open access journal, providing a platform for advances in basic ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

Your comments are very important to us

We welcome your ideas, suggestions, comments, or questions. To reach Editorial Board please use one of the methods provided below.
 

Emails:

info@scopub.com
editorinchief@ejmanager.com

Office Address:
14 Rue de Grand-Bigard,
1082 Brussels
Belgium
 
We will respond within 48 to 72 hours.
 
Change of address or personal information? Please visit your account at www.ejmanager.com to update your information.